Reaktion #65689

ord-20119507813748e3abdff4e223ab7956

Reaktionsgleichung

Oc1cccc(Br)c1
m-Bromophenol
O=C1CCCO1
γ-butyrolactone
Brc1ccc2c(c1)OCCCC2
8-bromo-2,3,4,5-tetrahydro-1-benzoxepine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

m-Bromophenol was reacted with γ-butyrolactone in analogy to Example 17, paragraphs B, C and D, to give 8-bromo-2,3,4,5-tetrahydro-1-benzoxepine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05420273uspto-grants-1995_05