Reaktion #6567

Reaktionsgleichung

6,6-difluoro-5-trifluoromethyl-1-tert-butylsilyloxy-5-hexene

→

6,6-Difluoro-5-trifluoromethyl-5-hexenol

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe ion exchange resin was then filtered off
2. 2
   Waschenwashed with methanol
3. 3
   EinengenThe filtrate was carefully concentrated in a rotary evaporator (bath temperature=35° C.; 200 mbar)
4. 4
   SonstigeThe residue was used without further purification

Vorschrift

A solution of 3.59 g (11.28 mmol) 6,6-difluoro-5-trifluoromethyl-1-tert-butylsilyloxy-5-hexene in 50 ml methanol was treated with a teaspoon full of ion exchange resin and the mixture stirred for 3 hours at room temperature. The ion exchange resin was then filtered off and washed with methanol. The filtrate was carefully concentrated in a rotary evaporator (bath temperature=35° C.; 200 mbar). The residue was used without further purification.

Quelle