Reaktion #6565

Reaktionsgleichung

Thionyl chloride

product

6,6-Difluoro-5-hexenoic acid

→

6,6-Difluoro-5-hexenoyl chloride

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture heated
2. 2
   Temperaturunder reflux for 6 hours
3. 3
   workup.DISTILLATIONIt was then distilled under reduced pressure

Vorschrift

10.23 ml (140.68 mmol) Thionyl chloride was added dropwise to 8.0 g (52.29 mmol) of the product of Example 9 at room temperature. A drop of dimethylformamide was added and the mixture heated under reflux for 6 hours. It was then distilled under reduced pressure.

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