Reaktion #65645

Reaktionsgleichung

cyclohexylamine

atropic acid

N-methylmorpholine

iso-butyl chloroformate

→

product

Ausbeute 28.9%

N-Cyclohexyl-2-phenylpropenamide

Ausbeute 28.9%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe crude product was purified by recrystallisation from cyclohexane

Vorschrift

This compound was made from atropic acid (10.48 g, 70.8 mmol), N-methylmorpholine (7.8 ml, 70.9 mmol), iso-butyl chloroformate (9.2 ml, 70.9 mmol), and cyclohexylamine (8.1 ml, 70.7 mmol) using the procedure described in Example 3. The crude product was purified by recrystallisation from cyclohexane to give the product (4.69 g), as white crystals, m.p. 131°-133°. (Found: C, 78.7; H, 8.8; N, 5.95. C15H19NO requires C, 78.6; H, 8.35; N, 6.1%.)

Quelle