Reaktion #655818

ord-2f3f521677a740cab19f1c542f1a968b

Reaktionsgleichung

COc1cccc(Cl)c1Cl
2,3-dichloroanisole
Cc1ccccc1C(=O)Cl
o-toluoyl chloride
[Al+3].[Cl-].[Cl-].[Cl-]
AlCl3
→
COc1ccc(C(=O)c2ccccc2C)c(Cl)c1Cl
2,3-dichloro-4-methoxy-2'-methylbenzophenone

Edukte

COc1cccc(Cl)c1Cl
2,3-dichloroanisole
Cc1ccccc1C(=O)Cl
o-toluoyl chloride
[Al+3].[Cl-].[Cl-].[Cl-]
AlCl3

Reagenzien

Keine

Lösungsmittel

ClCCCl
1,2-dichloroethane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The Friedel-Crafts procedure of Example 24a is repeated with 35.4 g of 2,3-dichloroanisole, 32.4 g of o-toluoyl chloride and 28 g of AlCl3 being combined in 125 ml of 1,2-dichloroethane to yield a product of 2,3-dichloro-4-methoxy-2'-methylbenzophenone.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04728662uspto-grants-1988_03