Reaktion #655679

Reaktionsgleichung

6-bromo-benz[cd]indole-2-thiol

4-(1H-imidazol-1-yl)butanamine dihydrochloride

potassium hydroxide

→

desired product

6-Bromo-N-[4-(1H-imidazol-1-yl)butyl]benz[cd]indol-2-amine

Lösungsmittel

ethanol

Reaktionsbedingungen

Vorschrift

A mixture 4.2 g of 4-(1H-imidazol-1-yl)butanamine dihydrochloride in 75 ml of ethanol was treated with 2.2 g of potassium hydroxide and stirred for 18 hours. A 5.2 g portion of 6-bromo-benz[cd]indole-2-thiol and 6.4 g of mercuric acetate were added and the reaction proceeded as described in Example 1, giving 3.7 g of the desired product, mp 145°-147° C.

Quelle