Reaktion #65564

Reaktionsgleichung

2-(1-naphthyl)acetonitrile

dimethyl carbonate

sodium

methanol

→

2-(1-naphthyl)-2-(methoxycarbonyl)acetonitrile

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe solution is heated to reflux
2. 2
   Sonstigeevaporates off
3. 3
   TemperaturThe reaction medium is kept refluxing for 1 hour
4. 4
   Sonstigethe excess dimethyl carbonate is then evaporated off to dryness

Vorschrift

0.1 mol of 2-(1-naphthyl)acetonitrile is dissolved in 120 cm3 of dimethyl carbonate, and the solution is heated to reflux. 0.1 mol of sodium is then added in small portions over 30 min, during which time the methanol evaporates off. The reaction medium is kept refluxing for 1 hour, and the excess dimethyl carbonate is then evaporated off to dryness. The residue is taken up with 100 cm3 of an 18% solution of acetic acid in water.

Quelle