Reaktion #655318

ord-e39a6ff142a34425999cf22eda600e83

Reaktionsgleichung

CCCCn1c(=O)c2[nH]c([N+](=O)[O-])nc2n(CCCC)c1=O
1,3-di-n-butyl-8-nitro xanthine
Br
hydrobromic acid
→
CCCCn1c(=O)c2[nH]c(Br)nc2n(CCCC)c1=O
title product
CCCCn1c(=O)c2[nH]c(Br)nc2n(CCCC)c1=O
1,3-Di-n-butyl-8-bromo xanthine

Edukte

CCCCn1c(=O)c2[nH]c([N+](=O)[O-])nc2n(CCCC)c1=O
1,3-di-n-butyl-8-nitro xanthine
Br
hydrobromic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

1,3-Di-n-butyl-8-bromo xanthine was prepared from 1,3-di-n-butyl-8-nitro xanthine (0.5 g, 0.0016 mol) and concentrated hydrobromic acid (8 ml) using the procedure as described in Example 15. The title product was obtained after recrystallisation from ethanol, yield 0.4 g (91%), m.pt. 178° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06180791B2uspto-grants-2001_01