Reaktion #65513

Reaktionsgleichung

product

4-Hydroxy-3-(2-Propen-1-Yl)-Benzyl Alcohol

hydrogen

→

title compound

4-Hydroxy-3-Propylbenzyl Alcohol

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe reaction mixture was removed
2. 2
   Filtrationfiltered
3. 3
   Sonstigeevaporated in vacuo
4. 4
   SonstigeThe residue was purified on a silica gel flash chromatography column
5. 5
   Wascheneluted with 35% ethyl acetate/hexane

Vorschrift

To a solution of 0,370 g (2.25 mmol) of the product of Step E dissolved in 25 mL of absolute ethanol was added 53 mg of a 5% rhodium on carbon catalyst and the mixture was shaken under a 40 psig pressure of hydrogen on a Parr apparatus. After 30 minutes, the reaction mixture was removed, filtered and evaporated in vacuo. The residue was purified on a silica gel flash chromatography column eluted with 35% ethyl acetate/hexane to afford the title compound.

Quelle