Reaktion #65484

Reaktionsgleichung

product

(2-butyl pyrazolo (1,5-a)pyridin-3-yl) carbonyl benzonitrile

sulfuric acid

acetic acid

→

4-[(2-butyl pyrazolo(1,5-a) pyridin-3-yl) carbonyl]benzoic acid

Lösungsmittel

water

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 2 hours
2. 2
   Temperaturthe mixture was cooled down
3. 3
   Filtrationfiltered
4. 4
   Waschenwashed with water
5. 5
   Sonstigedried at 80° C. under reduced pressure

Vorschrift

A mixture of 845 mg of the product of Example 2 and 15 ml of a mixture in equal proportions of sulfuric acid, acetic acid and water was refluxed for 2 hours and the mixture was cooled down, taken up in water, filtered, washed with water and dried at 80° C. under reduced pressure.

Quelle