Reaktion #65455

ord-88a804730c8f403b9a86619d14d18910

Reaktionsgleichung

COc1ccc(CN2CCNCC2)c(OC)c1OC
1-(2,3,4-trimethoxybenzyl)piperazine
O=C(O)C1=COc2ccc(O)cc2O1
7-hydroxy-1,4-benzodioxin-2-carboxylic acid
→
COc1ccc(CN2CCN(C(=O)C3=COc4ccc(O)cc4O3)CC2)c(OC)c1OC
7-HYDROXY-2-[4-(2,3,4-TRIMETHOXYBENZYL)PIPERAZIN-1-YLCARBONYL]-1,4-BENZODIOXIN
Ausbeute 73.0%

Edukte

COc1ccc(CN2CCNCC2)c(OC)c1OC
1-(2,3,4-trimethoxybenzyl)piperazine
O=C(O)C1=COc2ccc(O)cc2O1
7-hydroxy-1,4-benzodioxin-2-carboxylic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThat compound is obtained in a yield of 73%

Vorschrift

That compound is obtained in a yield of 73% starting from 1-(2,3,4-trimethoxybenzyl)piperazine and 7-hydroxy-1,4-benzodioxin-2-carboxylic acid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05420132uspto-grants-1995_05