Reaktion #652206

Reaktionsgleichung

methyl 1-methoxy-2-indolecarboxylate

guanidine hydrochloride

sodium methoxide

→

1-methoxy-2-indoloylguanidine hydrochloride

Ausbeute 24.9%

Lösungsmittel

methanol

Reaktionsbedingungen

Vorschrift

The reaction was carried out in a manner similar to Example 1 except for using 0.46 g (2.24 mmol) of methyl 1-methoxy-2-indolecarboxylate, 2.14 g (22.4 mmol) of guanidine hydrochloride and 15 ml of a methanol solution of 1.21 g (22.4 mmol) of sodium methoxide. Thus 0.15 g (24.9%) of 1-methoxy-2-indoloylguanidine hydrochloride was obtained.

Quelle