Reaktion #652204

Reaktionsgleichung

methyl 1-hydroxy-2-indolecarboxylate

guanidine hydrochloride

sodium methoxide

→

1-Hydroxy-2-indoloylguanidine hydrochloride

Lösungsmittel

methanol

Reaktionsbedingungen

Vorschrift

The reaction was carried out in a manner similar to Example 1 except for using 1.00 g (5.23 mmol) of methyl 1-hydroxy-2-indolecarboxylate, 5.00 g (52.3 mmol) of guanidine hydrochloride and 50 ml of a methanol solution of 2.82 g (52.3 mmol) of sodium methoxide. 1-Hydroxy-2-indoloylguanidine hydrochloride was obtained in an amount of 0.56 g (42.0%).

Quelle