Reaktion #65175

ord-d6d03136904b410ca907b60713eb9a64

Reaktionsgleichung

CN1CCC(Sc2c[nH]c3ccc(Br)cc23)CC1
5-bromo-3[(1-methylpiperidin-4-yl)thio]-1H-indole
CCCCI
iodobutane
→
CCCCn1cc(SC2CCN(C)CC2)c2cc(Br)ccc21
5-bromo-1-butyl-3-[(1-methylpiperidin-4-yl)thio]1H-indole

Edukte

CN1CCC(Sc2c[nH]c3ccc(Br)cc23)CC1
5-bromo-3[(1-methylpiperidin-4-yl)thio]-1H-indole
CCCCI
iodobutane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared

Vorschrift

Prepared as described in Example 56 by reaction of 5-bromo-3[(1-methylpiperidin-4-yl)thio]-1H-indole (prepared in Example 44) with iodobutane.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05418242uspto-grants-1995_05