Reaktion #65140

Reaktionsgleichung

1,2-dihydro-2,2-dimethyl-6-nitro-3-(4H)-quinoxalinone

→

6-amino-1,2-dihydro-2,2-dimethyl-3-(4H)-quinoxalinone

Lösungsmittel

CH3OH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter the starting material is consumed
2. 2
   Filtrationthe solution is filtered
3. 3
   Einengenconcentrated in vacuo

Vorschrift

A solution of 1,2-dihydro-2,2-dimethyl-6-nitro-3-(4H)-quinoxalinone (663 mg, 3 mmol) in CH3OH (10 ml) is hydrogenated with 50 psi H2 (g) at room temperature in the presence of a catalyst of 10% by weight palladium on charcoal (50 mg). After the starting material is consumed, the solution is filtered and concentrated in vacuo to yield 6-amino-1,2-dihydro-2,2-dimethyl-3-(4H)-quinoxalinone.

Quelle