Reaktion #64972

Reaktionsgleichung

7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

NaOH

K2CO3

→

1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionextracted several times with CHCl3
2. 2
   Trocknenthe extract is dried over K2CO3
3. 3
   Einengenconcentrated
4. 4
   workup.DISTILLATIONthe residue is distilled

Vorschrift

11.8 g (64mmol) of 7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane are heated under reflux with 12 g of NaOH in 36 ml of water overnight. The mixture is saturated with K2CO3 and extracted several times with CHCl3, the extract is dried over K2CO3 and concentrated and the residue is distilled.

Quelle