Reaktion #64859

Reaktionsgleichung

trans-1,4-dibromo-2-butene

potassium phthalimide

→

title product

TRANS-1-BROMO-4-PHTHALIMIDO-2-BUTENE

Lösungsmittel

dimethyl formamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThen the reaction mixture was concentrated in vacuo
2. 2
   workup.DISSOLUTIONdissolved in ethyl acetate
3. 3
   Waschenwashed with brine

Vorschrift

A mixture of trans-1,4-dibromo-2-butene (6.4 g, 30 mmol) and potassium phthalimide (5.6 g, 30 mmol) in anhydrous dimethyl formamide (200 ml) was heated at 50° C. for 24 h. Then the reaction mixture was concentrated in vacuo, dissolved in ethyl acetate, washed with brine and the pure title product was obtained by flash chromatography on silica gel (ethyl acetate: hexane; 15:85) (3.2 g, 40%).

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