Reaktion #64830

Reaktionsgleichung

3-allyl-4-hydroxy-5-methoxybenzaldehyde

potassium carbonate

1-bromobutane

→

3-allyl-4-butoxy-5-methoxybenzaldehyde

Ausbeute 98.8%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas maintained at 40°-45° C. for three hours
2. 2
   Sonstigethe oil formed
3. 3
   Extraktionextracted with dichloromethane
4. 4
   WaschenAfter washing with water
5. 5
   Sonstigedrying
6. 6
   Sonstigeevaporation of the solvent
7. 7
   Sonstigea brown oil was obtained which

Vorschrift

A mixture of 3-allyl-4-hydroxy-5-methoxybenzaldehyde (10.25 g, 0.053 mole), dimethylformanide (150 ml), potassium carbonate (8.29 g, 0.06 mole) and 1-bromobutane (8.22 g, 0.06 mole) was maintained at 40°-45° C. for three hours. The reaction mixture was plunged into iced water and the oil formed extracted with dichloromethane. After washing with water, drying and evaporation of the solvent, a brown oil was obtained which was passed through a bed of silica 60 to give a pale yellow oil, 3-allyl-4-butoxy-5-methoxybenzaldehyde (13 g, yield=91%).

Quelle