Reaktion #647406

ord-d3933f597ff44c0eb91d5bb26fd1c4e9

Reaktionsgleichung

CCc1ccc(C(Cl)C(=O)C(=O)OC)cc1
3-chloro-3-(4-ethyl-phenyl)-2-oxo-propionic acid methyl ester
CC(N)=S
thioacetamide
→
CCc1ccc(-c2sc(C)nc2C(=O)OC)cc1
5-(4-Ethyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl Ester

Edukte

CCc1ccc(C(Cl)C(=O)C(=O)OC)cc1
3-chloro-3-(4-ethyl-phenyl)-2-oxo-propionic acid methyl ester
CC(N)=S
thioacetamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

prepared by reaction of 3-chloro-3-(4-ethyl-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.98 min; [M+H]+=262.1.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08063099B2uspto-grants-2011_11