Reaktion #64673

Reaktionsgleichung

1-Chloro-4-hydroxythioxanthone

potassium carbonate

n-Propyl bromide

→

title compound

Ausbeute 75.5%

1-Chloro-4-n-propoxythioxanthone

Ausbeute 75.5%

Lösungsmittel

acetone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe resulting mixture heated
2. 2
   Temperaturunder reflux for 16 hours
3. 3
   TemperaturThe mixture was then cooled
4. 4
   Sonstigequenched on to water (250 ml)
5. 5
   FiltrationThe solid was filtered
6. 6
   Waschenwashed with water the resulting damp solid
7. 7
   Sonstigerecrystallised from ethanol (50 ml)

Vorschrift

1-Chloro-4-hydroxythioxanthone (7.8 g; 0.03 mol) prepared as above and potassium carbonate (5.0 g; 0.036 mol) was stirred and refluxed for 10 minutes in acetone (50 ml). n-Propyl bromide (5.5 g; 0.045 mol) was added and the resulting mixture heated under reflux for 16 hours. The mixture was then cooled and quenched on to water (250 ml). The solid was filtered and washed with water the resulting damp solid recrystallised from ethanol (50 ml) to afford the title compound (6.9 g; 75.5%) of mp 102°-3°. Analysis C16H13ClO2S=304.777 Requires C 63.05%; H 4.30%; Cl 11.63%; S 10.52% Found C 63.14%; H 4.37%; Cl 11.66%; S 10.63%

Quelle