Reaktion #646409

ord-0bded5c75f3e451aaea165acd55efab5

Reaktionsgleichung

Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4ccn(CCO)n4)ccc3n(C)c21
3-(2,4-dichlorophenyl)-6-[1-(2-hydroxyethyl)-1H-pyrazol-3-yl]-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one
CCOCCBr
2-bromoethyl ethyl ether
→
CCOCCOCCn1ccc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)n1
3-(2,4-Dichlorophenyl)-6-{1-[2-(2-ethoxyethoxy)ethyl]-1H-pyrazol-3-yl}-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one

Edukte

—
compound
Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4ccn(CCO)n4)ccc3n(C)c21
3-(2,4-dichlorophenyl)-6-[1-(2-hydroxyethyl)-1H-pyrazol-3-yl]-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one
CCOCCBr
2-bromoethyl ethyl ether

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The process is carried out as in Example 101 above, with the compound from Example 51, 3-(2,4-dichlorophenyl)-6-[1-(2-hydroxyethyl)-1H-pyrazol-3-yl]-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and 2-bromoethyl ethyl ether.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08063061B2uspto-grants-2011_11