Reaktion #646403

ord-03691fb1b6f3444fbc4cc57c2d632e8e

Reaktionsgleichung

CN(C)C=CC(=O)c1ccc2c(c1)c1cc(-c3ccc(Cl)cc3Cl)c(=O)n(C)c1n2C
3-(2,4-dichlorophenyl)-6-(3-dimethylaminoacryloyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one
CNN
methylhydrazine
→
Cn1nccc1-c1ccc2c(c1)c1cc(-c3ccc(Cl)cc3Cl)c(=O)n(C)c1n2C
3-(2,4-Dichlorophenyl)-1,9-dimethyl-6-(2-methyl-2H-pyrazol-3-yl)-1,9-dihydropyrido[2,3-b]indol-2-one

Edukte

—
1.10F
CN(C)C=CC(=O)c1ccc2c(c1)c1cc(-c3ccc(Cl)cc3Cl)c(=O)n(C)c1n2C
3-(2,4-dichlorophenyl)-6-(3-dimethylaminoacryloyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one
CNN
methylhydrazine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The process is carried out as in Example 37 above, with the compound from preparation 1.10F, 3-(2,4-dichlorophenyl)-6-(3-dimethylaminoacryloyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and methylhydrazine

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08063061B2uspto-grants-2011_11