Reaktion #646359

ord-99386d1b6fe44fb5813f11ad4308b9da

Reaktionsgleichung

Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4ccn[nH]4)ccc3n(C)c21
3-(2,4-dichlorophenyl)-1,9-dimethyl-6-(1H-pyrazol-5-yl)-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one
ClCCN1CCOCC1
chloroethylmorpholine
→
Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4ccn(CCN5CCOCC5)n4)ccc3n(C)c21
3-(2,4-Dichlorophenyl)-1,9-dimethyl-6-[1-(2-morpholin-4-ylethyl)-1H-pyrazol-3-yl]-1,9-dihydropyrido[2,3-b]indol-2-one

Edukte

Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4ccn[nH]4)ccc3n(C)c21
3-(2,4-dichlorophenyl)-1,9-dimethyl-6-(1H-pyrazol-5-yl)-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one
ClCCN1CCOCC1
chloroethylmorpholine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The process is carried out as in Example 36, using compound 3-(2,4-dichlorophenyl)-1,9-dimethyl-6-(1H-pyrazol-5-yl)-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one from Example 39 above and chloroethylmorpholine

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08063061B2uspto-grants-2011_11