Reaktion #64591

Reaktionsgleichung

anthranilic acid

n-octyl p-toluenesulfonate

sodium hydroxide

→

N-n-octylanthranilic acid

Ausbeute 43.1%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwas added
2. 2
   Einengenthe toluene layer was concentrated

Vorschrift

To a solution of anthranilic acid in toluene, n-octyl p-toluenesulfonate prepared according to the conventional method was added and the mixture was refluxed at 120° C. After 6 hours, an aqueous solution of sodium hydroxide was added and the toluene layer was concentrated. N-n-octylanthranilic acid was obtained from the remaining reactant after the purification by column chromatography with the yield of 43.1%.

Quelle