Reaktion #645231

Reaktionsgleichung

Toluene

tert-butyl formate

methacrylate

tert-butyl 6-methacryloyl-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furan-7-carboxylate

→

target compound

Ausbeute 90.0%

6-methacryloyl-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furan-7-carboxylic acid

Ausbeute 90.0%

Lösungsmittel

formic acid

formic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewere azeotroped off
2. 2
   SonstigeRecrystallization from hexane

Vorschrift

In 80 g of formic acid was dissolved 20.0 g of the methacrylate obtained in Example 1-1-1. The solution was stirred at room temperature overnight. Toluene was added to the reaction solution, from which formic acid and tert-butyl formate were azeotroped off. Recrystallization from hexane yielded 14.7 g of the target compound (yield 89%).

Quelle