Reaktion #64423

ord-f3528eb525984558858b648e2ac6c3f7

Reaktionsgleichung

O.[Na+].[OH-]
H2O NaOH
CCCCCCCNC(C)=O
N-heptylacetamide
[Al+3].[H-].[H-].[H-].[H-].[Li+]
lithium aluminum hydride
→
CCCCCCCNCC
N-heptyl-N-ethylamine

Edukte

O.[Na+].[OH-]
H2O NaOH
CCCCCCCNC(C)=O
N-heptylacetamide
[Al+3].[H-].[H-].[H-].[H-].[Li+]
lithium aluminum hydride

Reagenzien

Keine

Lösungsmittel

CCOCC
diethyl ether

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Trocknenis dried over MgSO4
  2. 2
    Filtrationfiltered
  3. 3
    Einengenconcentrated under vacuum

Vorschrift

A mixture of a solution of 5.5 gms of the N-heptylacetamide in 150 ml of diethyl ether and 3.99 gms of lithium aluminum hydride are stirred at room temperature for 18 hours. The reaction mixture is then worked up with H2O/NaOH by the Fieser method, following which the organic layer is dried over MgSO4, filtered, and concentrated under vacuum to give N-heptyl-N-ethylamine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05412137uspto-grants-1995_05