Reaktion #64356

Reaktionsgleichung

N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

ethyl iodide

hydride

tetrahydrofuran

Dichloromethane

→

N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Temperaturat reflux for 30 minutes
3. 3
   Sonstigeany insoluble matter was removed by filtration
4. 4
   SonstigeThe filtrate was recrystallized from a mixture of diethyl ether and n-hexane

Vorschrift

A mixture of 0.53 g of N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide, 1.60 g of ethyl iodide, 0.09 g of sodlum hydride, and 10 ml of tetrahydrofuran was heated at reflux for 30 minutes. Dichloromethane was added to the reaction mixture, and any insoluble matter was removed by filtration. The filtrate was recrystallized from a mixture of diethyl ether and n-hexane to obtain 0.45 g of N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide represented by formula shown below.

Quelle