Reaktion #64307

Reaktionsgleichung

4-bromobenzaldehyde

2,4-dimethylpent-3-ylamine

water

→

(4-bromobenzylidene)(1-isopropyl-2-methylpropyl)amine

Ausbeute 94.9%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Sonstigewas removed with a Dean-Stark trap
3. 3
   SonstigeThe toluene then was removed under vacuum and distillation of the remaining residue

Vorschrift

A mixture of 4-bromobenzaldehyde (7.3 g, 40.0 mmol), 2,4-dimethylpent-3-ylamine (4.8 g, 41.4 mmol), and para-toluenesulfonic acid (0.05 g, 0.29 mmol) in 125 mL of toluene was heated under reflux while water was removed with a Dean-Stark trap. The toluene then was removed under vacuum and distillation of the remaining residue gave (4-bromobenzylidene)(1-isopropyl-2-methylpropyl)amine (10.71 g) as a clear colorless oil.

Quelle