Reaktion #64294

Reaktionsgleichung

ammonia

methylene chloride

2-(oxetan-3-oxycarbonyl)phenylsulfonyl chloride

→

2-(Oxetan-3-oxycarbonyl)phenylsulfonamide

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Waschenwashing the organic phase with water
2. 2
   Sonstigedrying
3. 3
   Sonstigeevaporating it
4. 4
   Sonstigecrystallising the residue from a methylene chloride/diethyl ether mixture, 6.7 g of 2-(oxetan-3-oxycarbonyl)phenylsulfonamide of melting point 169° to 170° C.
5. 5
   Sonstigeare obtained

Vorschrift

2.5 g of ammonia are passed into a methylene chloride solution of 2-(oxetan-3-oxycarbonyl)phenylsulfonyl chloride (Example H6) at a temperature of 0° to 5° C. in the course of 45 minutes. By adding water to the reaction mixture, washing the organic phase with water, drying and evaporating it and crystallising the residue from a methylene chloride/diethyl ether mixture, 6.7 g of 2-(oxetan-3-oxycarbonyl)phenylsulfonamide of melting point 169° to 170° C. are obtained.

Quelle