Reaktion #6411

Reaktionsgleichung

sodium hydroxide

8-bromo-1-octene

ethyl p-hydroxybenzoate

potassium carbonate

hydrochloric acid

→

p-(7-octenyloxy)benzoic acid

Ausbeute 89.0%

Lösungsmittel

water

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONThereto added
2. 2
   Temperaturreflux
3. 3
   SonstigeAfter conclusion of the reaction
4. 4
   SonstigeThe generated precipitate was collected
5. 5
   Waschenwashed sufficiently with water
6. 6
   Sonstigedried
7. 7
   Sonstigeto obtain 10.8 g of the objective ether compound

Vorschrift

9.4 g of 8-bromo-1-octene, 9.0 g of ethyl p-hydroxybenzoate, and 7.6 g of potassium carbonate were refluxed in ethanol for 10 hours. Thereto added was an aqueous solution containing 2.4 g of sodium hydroxide, and then reflux was further continued for 10 hours. After conclusion of the reaction, the reaction solution was diluted with water, and the pH of the solution was lowered to 2 by dropping hydrochloric acid. The generated precipitate was collected, washed sufficiently with water, and dried, to obtain 10.8 g of the objective ether compound. (Yield: 89%)

Quelle