Reaktion #640589

Reaktionsgleichung

cyanogen bromide

(±)-trans-1,2-cyclohexanediamine

3,4-difluorobenzaldehyde

→

title compound

(±)-trans-1,3-Bis-(3,4-difluoro-benzyl)octahydro-benzoimidazol-2-ylideneamine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe reaction mixture was evaporated to dryness
2. 2
   Waschenthe crude product washed with ether
3. 3
   Sonstigerecrystallized from MeOH

Vorschrift

The title compound was prepared from (±)-trans-1,2-cyclohexanediamine and 3,4-difluorobenzaldehyde by Procedure C. After reacting with cyanogen bromide, the reaction mixture was evaporated to dryness and the crude product washed with ether and recrystallized from MeOH to give the title compound as the hydrogen bromide salt (mp 238-240° C.). MS (ES+) m/z 392 ([M+1]+, 100).

Quelle