Reaktion #638862

ord-0e9e500eab494ed9bb3506c7fcee9c65

Reaktionsgleichung

CC(C)(C)OC(=O)C[C@]1(C[N+](=O)[O-])C[C@@H]2CC=C[C@@H]21
( 1-c )
CC(C)(C)OC(=O)C[C@]1(C[N+](=O)[O-])C[C@@H]2CC=C[C@@H]21
Tert-butyl(±)-[(1S,5R,6R)-6-(nitromethyl)bicyclo[3.2.0]hept-3-en-6-yl]acetate
CC1=C(C)[C@H]2C(=CC(=O)OC(C)(C)C)C[C@H]2C1
tert-butyl(±)-(1S,5R)-[3,4-dimethylbicyclo[3.2.0]hept-3-en-6-ylidene]acetate
→
CC1=C(C)[C@H]2[C@@H](C1)C[C@]2(CC(=O)OC(C)(C)C)C[N+](=O)[O-]
Tert-butyl(±)-[(1S,5R,6R)-3,4-dimethyl-6-nitromethylbicyclo[3.2.0]hept-3-en-6-yl]acetate

Edukte

CC(C)(C)OC(=O)C[C@]1(C[N+](=O)[O-])C[C@@H]2CC=C[C@@H]21
( 1-c )
CC(C)(C)OC(=O)C[C@]1(C[N+](=O)[O-])C[C@@H]2CC=C[C@@H]21
Tert-butyl(±)-[(1S,5R,6R)-6-(nitromethyl)bicyclo[3.2.0]hept-3-en-6-yl]acetate
CC1=C(C)[C@H]2C(=CC(=O)OC(C)(C)C)C[C@H]2C1
tert-butyl(±)-(1S,5R)-[3,4-dimethylbicyclo[3.2.0]hept-3-en-6-ylidene]acetate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The compound of interest (4.5 g, 85%) was obtained as an oil substance in the same way as in paragraph (1-c) using tert-butyl(±)-(1S,5R)-[3,4-dimethylbicyclo[3.2.0]hept-3-en-6-ylidene]acetate (4.2 g, 18 mmol).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07947738B2uspto-grants-2011_05