Reaktion #63827

Reaktionsgleichung

2-[3-chloro-4-[(2,4-dichlorophenyl)hydroxymethyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione

thionyl chloride

→

2-[3-chloro-4-[chloro(2,4-dichlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione

Lösungsmittel

trichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONare added dropwise, during a period of 5 minutes
2. 2
   Temperaturat reflux temperature
3. 3
   SonstigeThe reaction mixture is evaporated in vacuo
4. 4
   workup.ADDITIONMethylbenzene is added
5. 5
   Sonstigethe whole is evaporated again

Vorschrift

To a stirred mixture of 16 parts of 2-[3-chloro-4-[(2,4-dichlorophenyl)hydroxymethyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione and 150 parts of trichloromethane are added dropwise, during a period of 5 minutes, 16 parts of thionyl chloride. Upon completion, stirring is continued for 3 hours at reflux temperature. The reaction mixture is evaporated in vacuo. Methylbenzene is added and the whole is evaporated again, yielding 2-[3-chloro-4-[chloro(2,4-dichlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione.

Quelle