Reaktion #63753

Reaktionsgleichung

2-[(2-pyridylmethyl)sulphinyl]benzimidazole

n-propyl mercaptan

hydrochloric acid

→

1-(2-benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeevaporated in vacuo
2. 2
   SonstigeThe residue is crystallized from ethanol/ether

Vorschrift

2.6 g of 2-[(2-pyridylmethyl)sulphinyl]benzimidazole are dissolved in 30 ml of tetrahydrofuran and treated with 1.0 ml of n-propyl mercaptan. 10 ml of 3N hydrochloric acid are added at an internal temperature of 40°. The mixture is stirred at 40° for 5 minutes and then evaporated in vacuo. The residue is crystallized from ethanol/ether. There is obtained 1-(2-benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride of melting point 144°-145°.

Quelle