Reaktion #63686

ord-8a24a87a7e6747d8b7da6b9b3d65e1b0

Reaktionsgleichung

CC(=O)NCc1cc(C(C)(C)C)cc(S(=O)(=O)Cl)c1O
2-acetamidomethyl-6-chlorosulfonyl-4-(1,1-dimethylethyl)-phenol
C1CCNC1
pyrrolidine
→
CC(C)(C)c1cc(CN)c(O)c(S(=O)(=O)N2CCCC2)c1.Cl
2-Aminomethyl-4-(1,1-dimethylethyl)-6-(1-pyrrolidinylsulfonyl)-phenol hydrochloride

Edukte

CC(=O)NCc1cc(C(C)(C)C)cc(S(=O)(=O)Cl)c1O
2-acetamidomethyl-6-chlorosulfonyl-4-(1,1-dimethylethyl)-phenol
C1CCNC1
pyrrolidine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

This compound is prepared analogously to Examples 11 c and 11 d from 2-acetamidomethyl-6-chlorosulfonyl-4-(1,1-dimethylethyl)-phenol and pyrrolidine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04766241uspto-grants-1988_08