Reaktion #63677

Reaktionsgleichung

5,6,7,8-tetrahydro-2-naphthol methyl ether

chlorosulfonic acid

→

3-Chlorosulfonyl-5,6,7,8-tetrahydro-2-naphthol methyl ether

Lösungsmittel

methylene chloride

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe organic phase is separated off
2. 2
   Trocknendried with MgSO4
3. 3
   SonstigeThe solvent is removed by evaporation
4. 4
   Sonstigethe residue is recrystallized from acetone/petroleum ether

Vorschrift

118 g (0.73 mole) of 5,6,7,8-tetrahydro-2-naphthol methyl ether are dissolved in 320 ml of methylene chloride, and 177 ml of chlorosulfonic acid in 160 ml of methylene chloride are added. The mixture is stirred for 10 minutes at 5° C. and is poured into ice water. The organic phase is separated off and dried with MgSO4. The solvent is removed by evaporation and the residue is recrystallized from acetone/petroleum ether.

Quelle