Reaktion #63673

Reaktionsgleichung

3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride

ammonia

→

3-(1,1-Dimethylethyl)-6-methoxybenzenesulfonamide

Lösungsmittel

acetone

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationAfter acidification with concentrated hydrochloric acid the product is filtered off with suction
2. 2
   SonstigeIt is recrystallized from isopropanol

Vorschrift

25.3 g (0.1 mole) of 3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride are dissolved in a little acetone and the solution is added dropwise slowly, at room temperature, to 100 ml of concentrated ammonia solution. The mixture is stirred for 30 minutes at room temperature and poured into ice water. After acidification with concentrated hydrochloric acid the product is filtered off with suction. It is recrystallized from isopropanol.

Quelle