Reaktion #63672

Reaktionsgleichung

4-(1,1-dimethylethyl)anisole

chlorosulfonic acid

→

3-(1,1-Dimethylethyl)-6-methoxybenzenesulfonyl chloride

Lösungsmittel

methylene chloride

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONare added dropwise
2. 2
   SonstigeThe organic phase is separated off
3. 3
   Waschenwashed with water
4. 4
   Trocknendried with MgSO4
5. 5
   Einengenconcentrated

Vorschrift

12.3 g (0.075 mole) of 4-(1,1-dimethylethyl)anisole, dissolved in 30 ml of methylene chloride, are added dropwise, while cooling with ice, to 16.5 ml of chlorosulfonic acid, dissolved in 20 ml of methylene chloride. The mixture is stirred for 40 minutes and is then poured into ice water. The organic phase is separated off, washed with water, dried with MgSO4 and concentrated.

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