Reaktion #63282

ord-e0a55bbd18f149efb6cadcc27278e15e

Reaktionsgleichung

Cc1ccccc1C(CCN1CCCCC1)NC(=O)Cc1ccc2ccccc2n1
N-[1-(2-methylphenyl)-3-piperidinopropyl]quinaldinamide
O=C(O)/C=C/C(=O)O
fumaric acid
→
Cc1ccccc1C(CCN1CCCCC1)NC(=O)Cc1ccc2ccccc2n1.O=C(O)/C=C/C(=O)O
subject compound
Ausbeute 74.0%
Cc1ccccc1C(CCN1CCCCC1)NC(=O)Cc1ccc2ccccc2n1.O=C(O)/C=C/C(=O)O
N-[1-(2-methylphenyl)-3-piperidinopropyl]quinaldinamide fumarate
Ausbeute 74.0%

Edukte

Cc1ccccc1C(CCN1CCCCC1)NC(=O)Cc1ccc2ccccc2n1
N-[1-(2-methylphenyl)-3-piperidinopropyl]quinaldinamide
O=C(O)/C=C/C(=O)O
fumaric acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The procedure of Example 11 was repeated using 736 mg (1.9 mmol.) of N-[1-(2-methylphenyl)-3-piperidinopropyl]quinaldinamide and 220 mg (1.9 mmol.) of fumaric acid, to obtain 708 mg (yield: 74%) of the subject compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04764617uspto-grants-1988_08