Reaktion #63217

Reaktionsgleichung

t-butyl [2-(3-methyl-4-nitropyridine-2-carboxamido)ethyl]carbamate

trifluoroacetic acid

hydrochloride

→

N-(2-aminoethyl)-3-methyl-4-nitropyridine-2-carboxamide hydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas recrystallized from methanol/ether

Vorschrift

14.6 g of t-butyl [2-(3-methyl-4-nitropyridine-2-carboxamido)ethyl]carbamate were reacted with trifluoroacetic acid in an analogous manner to that described in Example 2, paragraph 2. The residue was converted into the hydrochloride which was recrystallized from methanol/ether, whereby there was obtained N-(2-aminoethyl)-3-methyl-4-nitropyridine-2-carboxamide hydrochloride as white crystals, m.p. 204°-205°.

Quelle