Reaktion #631971

ord-43b48e2ce5cd45609b530a2602e1348d

Reaktionsgleichung

C=CC(=O)OCCC(=O)O
2-Carboxyethyl acrylate
O=S(Cl)Cl
Thionyl chloride
→
C=CC(=O)OCCC(=O)Cl
desired product
C=CC(=O)OCCC(=O)Cl
3-chloro-3-oxopropyl acrylate

Edukte

C=CC(=O)OCCC(=O)O
2-Carboxyethyl acrylate
O=S(Cl)Cl
Thionyl chloride

Reagenzien

Keine

Lösungsmittel

ClCCl
CH2Cl2

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturthe solution is cooled in an ice bath
  2. 2
    SonstigeThe solvent is removed under reduced pressure

Vorschrift

2-Carboxyethyl acrylate (1 eq.) is dissolved in CH2Cl2 and the solution is cooled in an ice bath. Thionyl chloride (1 eq.) is added dropwise and the mixture is allowed to warm to room temperature and stir for 4 hours. The solvent is removed under reduced pressure and the desired product is isolated by vacuum distillation.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07935131B2uspto-grants-2011_05