Reaktion #631662

Reaktionsgleichung

2,2,6,6-tetramethyl-4-piperidone

acetone cyanohydrin

→

2,2,6,6-Tetramethyl-4-hydroxy-4-cyanopiperidine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto precipitate the desired cyanohydrin
2. 2
   SonstigeThe precipitate was collected
3. 3
   Waschenwashed with petroleum ether and air
4. 4
   Sonstigedried
5. 5
   Sonstigeto yield 70 g (61.4%)

Vorschrift

A solution of 97 g 2,2,6,6-tetramethyl-4-piperidone and 67 g of acetone cyanohydrin were stirred at room temperature for 30 hours to precipitate the desired cyanohydrin. The precipitate was collected, washed with petroleum ether and air dried to yield 70 g (61.4%); mp 129°-132° C.

Quelle