Reaktion #631387

Reaktionsgleichung

cyanoacetic acid

1-(2,6-dimethylphenyl)semicarbazide

acetic anhydride

→

N-(2-cyanoacetyl)-1-(2,6-dimethylphenyl)semicarbazide

Lösungsmittel

ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated to 80° for 2 hours
2. 2
   FiltrationThe reaction mixture is filtered
3. 3
   Waschenwashed with ether (3X)
4. 4
   Sonstigedried

Vorschrift

A mixture of 1 mole of cyanoacetic acid, 1 mole of 1-(2,6-dimethylphenyl)semicarbazide and 300 ml of acetic anhydride is heated to 80° for 2 hours. The mixture is cooled to RT, 50 ml of ether is added and it is stirred at RT overnight. The reaction mixture is filtered, washed with ether (3X) and dried to give N-(2-cyanoacetyl)-1-(2,6-dimethylphenyl)semicarbazide.

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