Reaktion #630751

Reaktionsgleichung

hydrogen chloride

3-bromo-4-difluoromethoxyaniline

1-methylcyclopropanecarbonyl chloride

pyridine

→

N-(3-bromo-4-difluoromethoxyphenyl)-1-methylcyclopropanecarboxamide

Ausbeute 96.0%

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Vorschrift

In the same manner as in Example 3 but using 3-bromo-4-difluoromethoxyaniline (2.4 g) and 1-methylcyclopropanecarbonyl chloride (1.2 g) with pyridine (0.8 g) as the hydrogen chloride-eliminating agent and ethyl acetate as the solvent, the operations were effected to give N-(3-bromo-4-difluoromethoxyphenyl)-1-methylcyclopropanecarboxamide (3.1 g). M.P., 71°-71.5° C.

Quelle