Reaktion #630342

Reaktionsgleichung

3-Dimethylcarbamoyloxypyridine

chloromethylbenzoate

→

3-(dimethylcarbamoyloxy)-1-(phenylcarbonyloxymethyl)pyridinium chloride

Ausbeute 85.2%

Lösungsmittel

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe precipitated solids were filtered off
2. 2
   Waschenwashed twice with anhydrous diethyl ether (100 ml×2)
3. 3
   SonstigeRecrystallization from acetone

Vorschrift

3-Dimethylcarbamoyloxypyridine (4.98 g) and chloromethylbenzoate (5.13 g) were heated to 70° C. with stirring for 4 hrs. The hot reaction mixture was poured into 100 ml of diethyl ether with vigorous stirring. The precipitated solids were filtered off and washed twice with anhydrous diethyl ether (100 ml×2). Recrystallization from acetone gave 8.6 g of 3-(dimethylcarbamoyloxy)-1-(phenylcarbonyloxymethyl)pyridinium chloride as prisms, m.p. 175°-176° C.

Quelle