Reaktion #6301

Reaktionsgleichung

Water

4[N-4-hydroxybutyl-N-butylamino]cinnamaldehyde

4-triflylbenzyltriphenylphosphonium bromide

n-BuLi

→

compound C

4-(N-4-hydroxybutyl-N-butylamino)-4'-triflyl 1,4-diphenyl-1,3-butadiene

Lösungsmittel

toluene

toluene

Reaktionsbedingungen

Vorschrift

To a stirred solution of 110 g (0.2 mole) of 4-triflylbenzyltriphenylphosphonium bromide in toluene is added dropwise 0.2 moles of n-BuLi at room temperature. After 2 hours a solution of 27.5 g (0.1 mole) of 4[N-4-hydroxybutyl-N-butylamino]cinnamaldehyde in toluene is added dropwise to the mixture, and the reaction is stirred for 18 hours at room temperature. Water is added, and compound C is isolated by vacuum filtration, washed with 60% ethanol/water, dried under vacuum, and purified by recrystallization from ethanol.

Quelle