Reaktion #62864

Reaktionsgleichung

sodium carbonate

3-amino-2,5-dichloro-4-methylbenzoic acid

MeOH

HCl

→

Methyl 3-amino-2,5-dichloro-4-methylbenzoate

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeis now passed in for 20 minutes
2. 2
   Temperaturunder reflux for a further 5 hours
3. 3
   TemperaturAfter cooling
4. 4
   SonstigeThe ester which has precipitated
5. 5
   Sonstigeis isolated
6. 6
   Sonstigedried

Vorschrift

30 g of 3-amino-2,5-dichloro-4-methylbenzoic acid are initially introduced into 140 ml of MeOH. HCl gas is now passed in for 20 minutes and the mixture is then boiled under reflux for a further 5 hours. After cooling, the mixture is poured into water and rendered alkaline with sodium carbonate. The ester which has precipitated is isolated and dried. Yield: 30.8 g, melting point: 53°-55°.

Quelle