Reaktion #62820

ord-fcd899a0ea594fffac41dad66a1efbd7

Reaktionsgleichung

CC(C(=O)OC1(C)CCCCC1)c1ccc2nc(N)sc2c1
1-methylcyclohexyl 2-amino-α-methylbenzothiazole-6-acetate
CC(C(=O)OC12CC3CC(CC(C3)C1)C2)c1ccc(N)cc1
1-adamantyl 2-(p-aminophenyl)propionate
→
CC(C(=O)OC12CC3CC(CC(C3)C1)C2)c1ccc2nc(N)sc2c1
1-adamantyl 2-amino-α-methylbenzothiazole-6-acetate
Ausbeute 83.0%

Edukte

CC(C(=O)OC1(C)CCCCC1)c1ccc2nc(N)sc2c1
1-methylcyclohexyl 2-amino-α-methylbenzothiazole-6-acetate
CC(C(=O)OC12CC3CC(CC(C3)C1)C2)c1ccc(N)cc1
1-adamantyl 2-(p-aminophenyl)propionate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigewere reacted

Vorschrift

Using the methpod similar to that used in the preparation of 1-methylcyclohexyl 2-amino-α-methylbenzothiazole-6-acetate, 19.1 g of 1-adamantyl 2-(p-aminophenyl)propionate were reacted to obtain 18.97 g (83% yield) of 1-adamantyl 2-amino-α-methylbenzothiazole-6-acetate as a creamy white solid melting at 151°-153° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04762840uspto-grants-1988_08