Reaktion #62816

Reaktionsgleichung

1-methylcyclohexyl 2-(p-nitrophenyl)-propionate

hydrogen

→

1-methylcyclohexyl 2-(p-aminophenyl)-propionate

Ausbeute 67.1%

Lösungsmittel

—

petroleum ether

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe catalyst was filtered off through celite
2. 2
   Sonstigethe filtrate was evaporated to dryness

Vorschrift

A stirred solution of 34.9 g of 1-methylcyclohexyl 2-(p-nitrophenyl)-propionate in 250 ml of absolute ethanol was hydrogenated at atmospheric pressure in the presence of 10% palladium on carbon catalyst. After the uptake of hydrogen gas was complete, the catalyst was filtered off through celite and the filtrate was evaporated to dryness. Trituration of the residue with petroleum ether gave 21.02 g (67% yield) of 1-methylcyclohexyl 2-(p-aminophenyl)-propionate as creamy white crystals melting at 85°-87° C.

Quelle