Reaktion #62785

Reaktionsgleichung

Trichloroacetyl chloride

N-(3-chloro)allyl-N-methoxyethylamine

triethylamine

→

above-named product

Ausbeute 92.7%

N-(3-chloro)allyl-N-methoxyethyl trichloroacetamide

Ausbeute 92.7%

Lösungsmittel

dichloromethane

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction was kept at approximately 5° C. with an ice-water bath
2. 2
   workup.ADDITIONUpon completion of the addition
3. 3
   WaschenThe reaction mixture was then washed twice with saturated brine
4. 4
   Trocknendried with sodium sulfate
5. 5
   SonstigeRotary evaporation

Vorschrift

N-(3-chloro)allyl-N-methoxyethylamine (2.25 g, 0.015 mol) and 1.52 g (0.015 mol) triethylamine were stirred in 70 ml dichloromethane. The reaction was kept at approximately 5° C. with an ice-water bath. Trichloroacetyl chloride (2.73 g, 0.015 mol) in 10 ml dichloromethane was added dropwise to the cooled solution. Upon completion of the addition, the mixture was stirred at room temperature for 6 hours. The reaction mixture was then washed twice with saturated brine and dried with sodium sulfate. Rotary evaporation yielded 4.1 g of the above-named product.

Quelle